Perfluoroalkyl bromides (also known as bromofluorocarbons) are physiologically inert and are useful as X-ray contrast agents, especially for lung examinations [Chem. Eng. News 53 (1975), 36, 18]. With their low surface tension they penetrate small spaces and evenly wet healthy lung tissue.
When the ratio of the fluorine to other halogens in perfluoroalkyl halides is high, the toxicity can be quite low, especially for perfluoroalky bromides. Perfluoro-1-bromooctane [423-55-2] has an LD50 of greater than 64 mL/kg when administered into the gastrointestinal tract, and has little effect when instilled into the lungs [D. M. Long and co-workers, in R. Filler, ed., Biochemistry Involving Carbon–Fluoride Bonds, American Chemical Society, Washington, D.C., 1976, 171–189.]
Perfluorooctyl bromide [423-55-2], has one of the highest oxygen-dissolving capabilities among fluorinated liquids [Jean G. Riess, Oxygen Carriers (“Blood Substitutes”) - Raison d’Etre, Chemistry, and Some Physiology, Chem. Rev. 2001, 101, 2797-2919]
Perfluroalkyl bromides are readily emulsified and show great promise in various medical applications such as tissue oxygenation, chemotherapy, and radiographic imaging [K. C. Lowe, Adv. Mater., 87 (1991); T. M. S. Chang and R. P. Geyer, eds., Blood Substitutes, Marcel Dekker, Inc., New York, 1989].
Fluoryx’s Perfluoroalkyl bromides products are listed below:
Cat. # |
CAS # |
Common Name |
|---|---|---|
FC14-06 |
335-56-8 |
Perfluorohexyl bromide |
FC14-08 |
423-55-2 |
Perfluorooctyl bromide |
FC14-10 |
307-43-7 |
Perfluorodecyl bromide |
FC14-12 |
67193-90-2 |
Perfluorododecyl bromide |
Please click on the CAS# or Product Name for product details.
Copyright Fluoryx Inc. 2009